The question has great significance with regards to the possibilities for extraterrestrial life. I grew up watching Lost in Space and The Invaders and the original Star Trek, and later The X Files and Star Trek: The Next Generation and Doctor Who. But while those classic shows piqued my budding interest in exobiology, my training in actual biology taught me that whatever the aliens look like, they will almost certainly not be humans with odd facial protuberances and strange accents. How evolution plays out on other planets is impossible to say, but it's likely to be vastly different from the pathways taken by life on Earth. I still remember reading Stephen Jay Gould's essay "Replaying the Tape" from his excellent book on the Cambrian-age Burgess Shale fauna, Wonderful Life, and being blown away by the following passage:
You press the rewind button and, making sure you thoroughly erase everything that actually happened, go back to any time and place in the past -– say, to the seas of the Burgess Shale. Then let the tape run again and see if the repetition looks at all like the original. If each replay strongly resembles life’s actual pathway, then we must conclude that what really happened pretty much had to occur. But suppose that the experimental versions all yield sensible results strikingly different from the actual history of life? What could we then say about the predictability of self-conscious intelligence? or of mammals?His point was that a great deal of evolution appears to be contingent -- dependent on events and occurrences that would be unlikely to repeat in exactly the same way. And while there's no way to re-run the tape on the Earth, considering the issue of constraint vs. contingency has profound implications regarding what we're likely to find elsewhere in the universe. If we did find extraterrestrial life, would we even recognize it if we saw it?
So maybe anaerobic respiration isn't as efficient as aerobic respiration, but apparently it works well enough.
There are other features that deserve consideration, too. How many of the things we take for granted about animal life are ubiquitous not because they were the result of strong natural selection, but simply because one of our ancestors had those features and happened to be the one that survived? I'm guessing that having the sensory organs, central processing unit (brain), and the mouth clustered together at the anterior end of the animal will turn out to be common; it makes sense to have your perceptive equipment and your feeding apparatus pointing basically in the direction you're most likely to move. And speaking of movement, how that's accomplished is probably going to turn out to be fairly uniform everywhere, because there aren't that many ways to fashion an appendage for walking, flying, or swimming.
But what about symmetry? The vast majority of animals are bilaterally symmetric, meaning that there's only one axis of symmetry that divides the animal into mirror-image halves. (A few have radial symmetry, where any line through the center works -- jellyfish being the most obvious example.) Even animals like starfish, that seem to have some weird five-way symmetry, are actually bilateral; it's obvious if you look at starfish larva, and in fact is given away by the position of the sieve plate (the opening through which they draw in water), which is off-center.
True multiple-line symmetry doesn't seem to exist in the animal world, and even in science fiction most aliens are depicted as being nicely bilateral. An exception are the Antarctic Elder Things, an invention of H. P. Lovecraft, which have pentaradial symmetry -- further illustrating that as unpleasant a person as Lovecraft evidently was, he had a hell of an imagination.
One clue in all this is a discovery in South Australia that was described in a paper a while back in Proceedings of the National Academy of Sciences. Paleontologists found a fossil half the size of a grain of rice that is over half a billion years old, and is the oldest truly bilateral animal ever found -- meaning what we're looking at may be a very close cousin to the ancestor of all the current bilateral animals on Earth.
In "Discovery of the Oldest Bilaterian from the Ediacaran of South Australia," by Scott D. Evans and Mary L. Droser (of the University of California-Riverside), Ian V. Hughes (of the University of California-San Diego), and James G. Gehling (of the South Australia Museum Department of Paleontology), we read about Ikaria wariootia, a teardrop-shaped critter whose unprepossessing appearance belies its significance. This tiny little proto-worm might actually be our great-great-great (etc. etc. etc.) grandparent.
Of course, this doesn't solve the question of whether bilateral symmetry is constrained or not. My guess is that if it turns out to be, it will be because mirror-symmetry is easier to produce genetically. A lot of the homeotic genes (genes that guide the development of overall body plan) work by creating a gradient of some chemical or another, so the polarity of structures is established (head here, butt there, and so forth). It might simply be easier to establish a one-way gradient, with a high on one end and a low on the other, than one with multiple highs and lows arranged symmetrically.
Although we do manage to do a five-point gradient in the development of our fingers and toes, so it's doable. It just may not be common.
In any case, here we have a creature that may be the reason we're arranged bilaterally, whether or not it gives us any sort of advantage. Kind of humbling that we might come from a millimeter-wide burrowing scavenger. I guess that's okay, though, if it'll keep humanity from getting any cockier than it already is.












