Skeptophilia (skep-to-fil-i-a) (n.) - the love of logical thought, skepticism, and thinking critically. Being an exploration of the applications of skeptical thinking to the world at large, with periodic excursions into linguistics, music, politics, cryptozoology, and why people keep seeing the face of Jesus on grilled cheese sandwiches.
Showing posts with label homeopathy. Show all posts
Showing posts with label homeopathy. Show all posts

Wednesday, October 9, 2024

Quantum homeopathy

In response to a post I did a while back about the tendency of people to believe loony ideas if they're couched in ten-dollar vocabulary, a loyal reader of Skeptophillia sent me a link to a paper by one Lionel Milgrom, of Imperial College (London), that has turned this phenomenon into an art form.

The name of the paper?

"'Torque-Like' Action of Remedies and Diseases on the Vital Force and Their Consequences for Homeopathic Treatment."

ln it, we witness something pretty spectacular: an attempt to explain homeopathy based on quantum mechanics.

[Image is in the Public Domain]

I'm not making this up, and it doesn't seem like a spoof; in fact, the paper appeared in the open-access Journal of Alternative and Complementary Medicine.  Here's the opening paragraph:
Within the developing theoretical context of quantum macroentanglement, a mathematical model of the Vital Force (Vf) has recently been formulated.  It describes the Vf in terms of a hypothetical gyroscope with quantized angular momentum.  This enables the Vf's state of health to be represented in terms of a "wave function" derived solely from secondary symptom observables produced in response to disease or homeopathic remedies.  So far, this approach has illustrated the biphasal action of remedies, resonance phenomena arising out of homeopathic provings, and aspects of the therapeutic encounter.
So right out of the starting gate, he's talking about using the quantum interactions of a force no one has ever detected to explain a treatment modality that has been repeatedly found to be completely worthless.  This by itself is pretty impressive, but it gets better as it goes along:
According to this model, symptom expression corresponds to precession of the Vf "gyroscope."  Conversely, complete removal of symptoms is equivalent to cessation of Vf "precession."  However, if overprescribed or given in unsuitable potency, the curative remedy (which may also be formulated as a wave function but this time derived solely from changes in Vf secondary symptom observables) may cause the Vf to express proving symptoms.  Thus, with only observation of symptoms and changes in them to indicate, indirectly, the state of a patient's Vf, the safest treatment strategy might be for the practitioner to proceed via gradual removal of the symptoms.
When I read the last line, I was lucky that I wasn't drinking anything, because it would have ended up splattered all over my computer.  Yes!  By all means, if a sick person comes in to visit a health professional, the health professional should proceed by removing the sick person's symptoms!

Because proceeding by making the symptoms worse is kind of counterproductive, you know?

His talk about "overprescription" made me chuckle, too.  Because if you'll recall, the late James Randi demonstrated dozens of times that the result of consuming a whole bottle of a homeopathic remedy is... nothing.  On the other hand, since the homeopaths believe that the more dilute a substance is, the stronger it gets, maybe "overprescribing" means "prescribing less."

Which reminds me of the story about the guy who forgot to take his homeopathic remedy, and as a result died of an overdose.

*rimshot*

And if this isn't enough, Dr. Milgrom (yes, he has a Ph.D., astonishingly enough) has also published other papers, including "The Thermodynamics of Health, Healing, and Love" and "Toward a Topological Description of the Therapeutic Process."

What's next, "The Three-Body Problem: A Classical Mechanics Approach to Handling Love Affairs?"

I have to admit, though, that there's something almost charming about this guy's attempt to bring pseudoscience under the lens of physics.  His blathering on about imaginary "vital forces" and the precession of microscopic gyroscopes as a mechanism for disease is, if nothing else, creative.  While what he's claiming is complete bollocks, Dr. Milgrom's determination to keep soldiering on is kind of adorable.

The good news, of course, is that his papers are unlikely to convince anyone who isn't already convinced.  The only danger is the undeserved veneer of credibility that this sort of thing gives homeopathy in people whose minds aren't yet made up.  One can only hope that the thorough debunking of this fraudulent practice that has been done by actual scientific researchers will prove, in the end, to be more persuasive.

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Monday, September 23, 2024

A remedy against pseudoscience

I've got a medication for you to take.  Here are the ingredients:

  • nux vomica -- the seed of the plant Strychnos nux-vomica, the natural source of strychnine.
  • belladonna -- Atropa belladonna, also called deadly nightshade.
  • hydrastis -- another toxic plant, Hydrastis canadensis, better known as goldenseal.
  • kali bichromicum -- chemists call it potassium dichromate, and it's carcinogenic and causes contact dermatitis.
  • ephedra vulgaris -- an extract of the plant of the same name, which contains the dangerous stimulant ephedrine.
  • histaminum hydrochloricum -- the organic compound produced by the human body in response to an allergic reaction, which is responsible for much of the misery of allergies and colds.  (Thus -- antihistamines.)

If by this point you're getting worried that anyone would suggest ingesting any of these, much less a combination of all six, fear not: the manufacturer takes them, dissolves them in water, then dilutes the combined solution by a factor of ten, six times in a row.  By this time, what's left has one millionth the concentration of the original.  And in fact, the advertisement for this "remedy" reassuringly tells prospective customers that it "contains no ephedrine, pseudoephedrine, or alkaloids."

So, for twenty-five bucks, you too can purchase a spray bottle filled with a liquid containing no active ingredients whatsoever.

Oh, and I didn't tell you what it's supposed to cure; snoring.  It's called "SnoreStop," and you're supposed to squirt it up your nose.

People in the know (and certainly regular readers of Skeptophilia) will recognize this as a prime example of the pseudoscientific horseshit known as homeopathy, which -- for some reason -- is still a lucrative business.  You can find homeopathic "remedies" on pharmacy shelves pretty much everywhere; they come in liquid and tablet form, and are recognizable by the presence of a number like "10x" on the label (that's the dilution factor; 10x would be diluted to one part in ten billion).

[Image licensed under the Creative Commons Dr. Moumita Sahana, Homeopathy globules, CC BY-SA 4.0]

But what sets apart SnoreStop from even the common run of homeopathic "remedies" -- which aren't going to cure anything, but at least won't make you sicker -- is that SnoreStop nasal spray has been found to contain potentially dangerous numbers of pathogens, including yeasts, molds, and bacteria like Providencia rettgeri, which can cause pneumonia and bacterial meningitis.

The company that produces SnoreStop, Green Pharmaceuticals, was notified of this back in 2022, but did nothing to fix the problem; in fact, why this comes up now is it just came to light that instead of destroying the contaminated lots, they simply relabeled, repackaged, and sold them.  They've also been charged by the FDA for selling an unlicensed and unregulated drug designed to treat a specific disorder, without going through the approval process.  (I guess they forgot to put the "This product is not intended to treat or cure any disorder, disease, or ailment" disclaimer on the package, which seems to be some kind of Get-Out-Of-Jail-Free card for these charlatans.)

The problem is, even if SnoreStop is taken off the market -- even if Green Pharmaceuticals goes out of business -- it's only the tip of the iceberg.  Homeopathy scams people for millions of dollars yearly.  And despite my previous statement that at least most of these "remedies" don't make you sicker, there is real harm done, when people refuse conventional (i.e. effective) medical treatment for illnesses in favor of homeopathy and magical thinking.  (There's good evidence that computer entrepreneur Steve Jobs significantly hastened his death from cancer by foregoing medical treatment for "alternative medicine.")

I know, caveat emptor and all that sort of thing.  People are gonna make ill-informed decisions, and you can't legislate away stupidity.  But what the producers of homeopathic remedies are doing -- as well as homeopathic "doctors" -- is deliberately misleading sick people into risking their health by taking a thoroughly discredited pseudoscientific concoction that relies on nonsense like water molecules having a "memory."

The only remedy against pseudoscience is science.  Learn some -- preferably before you need to make decisions regarding your health.

Just remember what the inimitable Tim Minchin said, in his wonderful diatribe against alternative medicine called Storm: "There's a name for alternative medicine that works.  It's called... medicine."

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Wednesday, August 30, 2023

Diluted nonsense

Every time I think homeopathy can't get more ridiculous, I turn out to be wrong.

I thought they'd plunged to the bottom of the Crazy Barrel with their announcement of a remedy called "homeopathic water."  This is, unfortunately, exactly what it sounds like.  It's water diluted with water, then shaken up, then diluted again and again.

With water.

So I thought, "This is it.  It can't get any loonier than that."

I was very, very wrong, and found out the depth of my mistake at Frank van der Kooy's site Complementary Medicine -- Exposing Academic Charlatans, wherein we find out that watering water down with water is far from the nuttiest thing the homeopaths make "remedies" from.

Here are a few things that van der Kooy discovered form the basis of a homeopathic remedy:
  • Black holes.  Yes, I mean the astronomical object, and yes, I'm serious.  An amateur astronomer put a vial of alcohol on a telescope aimed at the location of Cygnus X-1, the first black hole to be discovered.  My guess is that said astronomer had consumed a good bit of the alcohol first, and that's how he got the idea.  But after the vial had sat there for a while, and gotten saturated with the Essence of Black Hole, it was diluted to "30C" (known to the rest of us as one part in ten to the thirtieth power).  The homeopaths say if you consume it, it causes you to have a "drawing inward" sensation (because, I'm guessing, black holes pull stuff in).  One person who tested it said it felt like her teeth were being pulled backwards into her head.  Why this is supposed to be a good thing, I have no idea.
  • Vacuum.  I'm not talking about the machine, I'm talking about the physical phenomenon.  I don't have a clue how you would mix a vacuum in water, nor what "diluting a vacuum" even means.  The "practitioner," however, says it's really good for treating the flu.
  • The note "F."  Why F and not C# or Ab or something, I'm not sure, but apparently this is made by playing the note F at some water, then diluting it a bunch.  After that, it's good as a "tranquilizer" and "cardiac regulator."
  • The south pole of a magnet.  Again, I'm not sure what's special about the south pole, but if you somehow introduce south-poliness into some water, you can use it to treat frostbite, hernia, dislocations, ingrown toenails, and "levitation."  (I feel obliged at this point to state again for the record that I'm not making this up.)
  • Dog shit.  Supposedly, consuming diluted dog shit helps you get over feelings of self-disgust, which you would definitely need if you're consuming diluted dog shit.  It also helps if you dream about dogs, or "feel like your arms and legs are getting shorter," which I didn't know was even a thing.
  • The Berlin Wall.  A remedy made from a chunk of the Wall -- and not to beat this point to death, but the Wall piece was shaken up in water and diluted a gazillion times -- is good for treating despair.  I could use some right now, because after reading about how many people believe this kind of thing works, I'm inclined to agree with Professor Farnsworth.

I really should stop reading stuff like this, because I really can't afford any further declines in my opinion about the general intelligence of the human species.

Once again, I'm struck not by people coming up with this nonsense, because selling nonsense to make money has been a pastime of humans for a long, long time.  What gets me is that apparently people read this stuff, and don't have the response that I did, which is to snort derisively and say, "You have got to be fucking kidding me."  Instead, they pull out their credit cards and start buying.

So here we are again, shaking our heads in utter bafflement.  At least I hope you are.  I hope you haven't read this and said, "What's he pissing and moaning for?  This all makes perfect sense."  If that was, in fact, your response, please don't tell me about it.  Now y'all will have to excuse me, because I'm going to go take my anti-despair Berlin Wall remedy, mixed well into a double scotch.  That might actually have some effect.

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Friday, August 5, 2022

Starve a cold

Today from the Unintentionally Hilarious Department, we have a paper that made its way into PubMed that has the title, "Pharmacoeconomic Comparison Between Homeopathic and Antibiotic Treatment Strategies in Recurrent Acute Rhinopharyngitis in Children."

[Image is in the Public Domain]

Here's a quick summary of the objectives and results, as quoted from the abstract:

Objectives: A pharmacoeconomic study to compare, in terms of: medical effectiveness, quality of life and costs two treatment strategies ('homeopathic strategy' vs 'antibiotic strategy') used in routine medical practice by allopathic and homeopathic GPs in the treatment of recurrent acute rhinopharyngitis in 18-month to 4-year-old children. 

Results: The 'homeopathic strategy' yielded significantly better results than the 'antibiotic strategy' in terms of medical effectiveness (number of episodes of rhinopharyngitis: 2.71 vs 3.97, P<0.001; number of complications: 1.25 vs 1.95, P<0.001), and quality of life (global score: 21.38 vs 30.43, P<0.001), with lower direct medical costs covered by Social Security (88 Euros vs 99 Euros, P<0.05) and significantly less sick-leave (9.5% of parents vs 31.6% of parents, P<0.001)...  Homeopathy may be a cost-effective alternative to antibiotics in the treatment of recurrent infantile rhinopharyngitis.
What makes this hilarious is that the authors of the article, Melanie Trichard, Gilles Chaufferin, and Nicolas Nicoloyannis, are apparently unaware that because acute rhinopharyngitis (better known to most of us as a "cold") is viral in origin, antibiotics are entirely useless for fighting it, and no competent doctor would prescribe them in this situation for a child or for anyone else.  So saying that homeopathic "remedies" are as good for fighting colds as antibiotics is akin to the following claims:
  • crystals are as effective as aromatherapy for setting broken bones
  • blood-letting has the same success rate as seeing a witch doctor for curing brain cancer
  • Tarot cards have the same likelihood of telling you your future as palm-reading
  • peanut butter is as effective as chocolate pudding as a window-cleaner
The maddening thing is that you can still find homeopathic "remedies" (i.e., pills or liquids with no active ingredients) being sold for lots of money on pharmacy shelves, despite study after study showing that they are worthless.  The most recent study generated the following conclusion:
The review found no good quality, well-designed studies with enough participants to support the idea that homeopathy works better than a placebo, or causes health improvements equal to those of another treatment. 
Although some studies did report that homeopathy was effective, the quality of those studies was assessed as being small and/or of poor quality.  These studies had either too few participants, poor design, poor conduct and or [sic] reporting to allow reliable conclusions to be drawn on the effectiveness of homeopathy. 
According to CEO Professor Warwick Anderson, “All medical treatments and interventions should be underpinned by reliable evidence. NHMRC’s review shows that there is no good quality evidence to support the claim that homeopathy works better than a placebo.”
Dr. Steven Novella, a vocal and articulate supporter of science-based medicine, put it more clearly:

[The] pattern is now clear – gold standard clinical evidence shows that homeopathy does not work.  Homeopaths do not respond by either producing high quality evidence of efficacy or by changing their views to account for the evidence.  Rather, they whine about the game being rigged against them and try to change the rules of evidence, so that weak studies that are almost guaranteed to be false positive are used, or studies that are not even designed to test efficacy... 
For some reason we cannot summon the political will to do what reason demands (and what multiple systematic reviews by government bodies have recommended) and finally expel homeopathy from modern health care. 
Still there are researchers, either because they are true believers or just naive, calling for yet more research into homeopathy, such as the proposed Toronto study of homeopathy for ADHD.  The demand for more research will never end.  The public, however, should no longer support this profound waste of resources.
What is amazing is that the homeopaths themselves won't admit that the game is up.  How many failed studies do they need?  I realize that this would mean they were out of a job, but for cryin' in the sink, at what point do you say, "Okay, I guess I was wrong?"

I guess the answer to the last question is, "Never."  "Death before admitting we're ripping people off by selling them useless remedies," that's the motto of the homeopaths.  Anyhow, I'm done here.  I've got to go clean my windows.  The last time didn't work out so well.

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Monday, August 31, 2020

Fighting visual malware with water

One of the things that baffles me about woo-woos is how they never, ever give up.

When I'm proven wrong, I usually (1) feel extremely embarrassed about it, and (2) retreat in disarray.  Oh, and (3) do everything I can to make sure I don't make the same error the next time.  I mean, everyone makes mistakes, so I probably shouldn't overreact to it the way I do; but I like to think that as a writer on science and skepticism, I'm conscientious enough to check my facts and sources.  Otherwise, I'm really no better than the people I rail against on a daily basis.

So getting caught out hits me where it hurts, you know?

Not so, apparently, in the woo-woo world.  You can be laughed into oblivion, and you just keep on moseying on ahead as if nothing was wrong.

As an especially good example of this, remember Dr. Charlene Werner?  She was the star of a viral YouTube video a few years back called "Crazy Homeopathy Lady," the title of which you'd think would be devastating enough.  In this video, she attempts to explain homeopathy thusly:
  • The mass in the universe is "infinitesimal."  Since mass is the "m" in E = mc2 , she says that because the mass is so small this crosses the "m" out, which means that "energy = light."  (The whole effect is accentuated by the fact that she pronounces the word "infant-esimal," which sounds like a descriptor for a really little baby.)
  • Something about "Stephen Hawkings" and vibrations and quantum.
  • Fascinating discourse on string theory, starting with the fact that strings are "little u-ies."
  • A bizarre analogy wherein she compares homeopathy's effects to a neighbor's dog pooping on your lawn, causing you to throw a bomb at your neighbor's house.
If you've never seen this video, I highly recommend it.  I can say from experience that it's even more fun to watch while drunk, although I won't be held responsible if you laugh so hard you fall out of your chair and spill scotch all over your carpet.

[Image is in the Public Domain]

So anyhow.  This video has received millions of views, and tens of thousands of comments, most of which were of the "Holy shit, this woman is insane" variety.  So you'd think that any normal human being who got this kind of feedback would sort of vanish from the public eye.  Most of us, in fact, would probably want to crawl under a rock.

Not so Charlene Werner.  She's baaaaaack, on a website called "Simply Healthy Self," wherein she makes statements that very nearly exceed the wackiness of the ones she made in the video.  Here's a sampler:
Imagine your vision system has qualities similar to a computer.  The photoreceptors are like your keys on your keyboard.  There are approximately 1.2 million of them in each eye.  When clicked or activated with light, the data from your 'visual keyboard' relays to your brain.  Your brain has characteristics similar to a hard drive with an operating system that runs all the 'software programs' or functions in your body, such as moving your eye muscles, tracking, focusing, and visual memory.  Even your heart, kidney, lungs, and all your bodily functions depend on accurate key strokes from your photoreceptors and other sensory input, access to your brain (hard drive), a powerful operating system, and efficient use of software programs.
Yup.  Your kidneys depend on information from your eyes.  Which explains why blind people never have to pee.
Homeopathy then scans your system to eliminate 'viruses' or 'malware', which are often belief systems or programmed patterns that interrupt your system's smooth functioning.
So a bottle of water with no active ingredients is the medical equivalent of Norton AntiVirus?  If only we'd realized sooner that these "remedies" can fix faulty belief systems, we might have avoided having our government turned into Corruption "R" Us by a man whose chief claim to fame seems to be embodying all Seven Deadly Sins in one individual.
When we consider the whole of man we can even make a further leap……that mass in the universe by definition is matter, matter is substance, the substance of man is cells, and cells can be broken down into compounds, compounds into elements, and elements into tiny particles of energy called electrons, protons, neutrons, and sub-atomic particles held together by an “invisible” force such that what may look like a physical body is merely energy.
An explanation which is to physics what "The foot-bone's connected to the shin-bone, the shin-bone's connected to the knee-bone" is to medical science.

Then we get bunches of testimonials about how Dr. Werner's treatments have cured everything from rheumatoid arthritis to bad eyesight to being lousy at sports.

Which is pretty impressive, because homeopathy has failed to show measurable results in every controlled study ever done.  Ever.  Clear enough?  What she's proposing is unscientific horse waste, and her "success stories" are the result of the placebo effect at best.

None of which, of course, is going to change a thing.  If the reception her bizarre YouTube video received didn't make her reconsider her position, nothing will.  Unfortunately, there are still people who buy what she's selling (literally and figuratively), although it's to be hoped that the support for such completely disproven modalities as homeopathy is waning.

The chance of convincing Dr. Werner, however, is "infant-esimal."

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This week's Skeptophilia book recommendation of the week should be in everyone's personal library.  It's the parting gift we received from the brilliant astrophysicist Stephen Hawking, who died two years ago after beating the odds against ALS's death sentence for over fifty years.

In Brief Answers to the Big Questions, Hawking looks at our future -- our chances at stopping anthropogenic climate change, preventing nuclear war, curbing overpopulation -- as well as addressing a number of the "big questions" he references in the title.  Does God exist?  Should we colonize space?  What would happen if the aliens came here?  Is it a good idea to develop artificial intelligence?

And finally, what is humanity's chance of surviving?

In a fascinating, engaging, and ultimately optimistic book, Hawking gives us his answers to the questions that occupy the minds of every intelligent human.  Published posthumously -- Hawking died in March of 2018, and Brief Answers hit the bookshelves in October of that year -- it's a final missive from one of the finest brains our species ever produced.  Anyone with more than a passing interest in science or philosophy should put this book on the to-read list.

[Note: if you purchase this book using the image/link below, part of the proceeds goes to support Skeptophilia!]



Tuesday, December 4, 2018

Medical care, serial dilution, and mathematical horses

It's been a while since we've seen a new salvo from the homeopaths, but I knew this did not mean they'd retreated in disarray.  After all, a belief in pseudoscientific woo-woo quackery means never having to say you're sorry.

The most recent news from the world of homeopathy comes from an online magazine called Clever H.  This is in many ways an unfortunate choice of names.  It immediately reminded me of "Clever Hans," a horse back in 1907 whose owner claimed he could do arithmetic.  Of course, the horse could do no such thing, but was shown by German psychologist Oskar Pfungst to be receiving cues from its owner.  Once the owner was taken off stage, suddenly Clever Hans lost his phenomenal ability to do calculations.

Clever Hans and his owner [Image is in the Public Domain]

So calling the magazine a name that recalls a debunked false claim isn't so much unflattering as it is ironic.  Apparently unaware of this, the writers are boundless in their enthusiasm, subtitling Clever H as "The Mag by Homeopaths, for Homeopaths, With the Patient in Mind!"  The article that caught my attention was called "The Anti-Aging of Homeopathic Cell Salts," which I at first thought meant they'd discovered a way to keep salt from aging.

Which, as far as I've heard, is not really a big problem.

But that isn't what the article's about.  It claims that they've discovered some chemicals ("cell salts") that can prevent, or even reverse, aging.  The authors write:
Tissue Salts are an off shoot of homeopathy and are vital elements that correspond to the same minerals our cells are made of.  These “vital elements” will nourish and rebuild your cells...   [A] homeopathic treatment that can be helpful in slowing the aging process and reducing the early signs of aging is a homeopathic detox of the liver, kidney and lymphatic system.  This will stimulate your body to function better.  A noticeable difference will be seen on the skin’s appearance and even aches and pains will improve.  When the lymphatic system is functioning at its best, weight loss and cellulite will be in control and the immune system will be functioning optimally.

Equipped with such homeopathic anti-aging secrets, the aging process can be slowed and life can be lived to the fullest beyond the days of youth.
Now, at the age of 58, no one would be happier than me to find there was a way to reverse aging.  (Physical aging, I mean.  My emotional age kind of plateaued around age 13, which is why I still laugh at fart jokes.)  On the other hand, I'm not so fond of the gray hair, wrinkles, and miscellaneous aches and pains, and would thrilled if I could return to the physique I had when I was 25.

What Clever H says we should do is take the homeopathic concoctions "calc fluor," "calc phos," and "kali phos," because all of these are valuable "cell salts" that will have the effect of restoring your youth.  Oh, and also "nat mur," which is a "water distributor."  Which, I suppose, is better than having water pool in our feet, or something.

So I did some research -- if you can dignify it by that name -- and found out that "calc fluor" is useful for treating hemorrhoids, "calc phos" restores health after an injury, "kali phos" is good for stress, and "nat mur" keeps you from drying out.  "Nat mur," I also found out, was made from plain old salt, so I was curious as to why they were making such a big deal about it.  In searching for an answer I stumbled upon a page about "nat mur" on the site of the British Homeopathic Organization, which had some information that was puzzling, to say the least:
The higher organisms, the mammals, require sodium chloride in comparatively large amounts.  It is clear that as life evolves to higher forms, and the faculties of perception and feeling unfold, the role of sodium chloride in psychological and biological functions becomes increasingly important.  The active secretion of salt through the urine, sweat and tears appeared in parallel with the development of feeling and the tender emotions.
So I'm supposed to develop tender emotions when I'm taking a piss?  Or am I missing some vital piece of the argument, here?

We also find out there are "nat mur" personalities, which are characterized by harshness, resentment, and lack of demonstrative emotions.  Because of the ocean or something.

 But back to the Clever H page, wherein we find that the recommended concentrations of all of these "remedies" are between "6x" and "30x."  For those of you who don't know how homeopathic "remedies" are produced, allow me to explain that each "x" represents a 1-in-10 dilution.  So a 6x dilution would have 1 part of the original substance dissolved in 1,000,000 parts of some inert substance like water or a sugar pill.  So that's pretty dilute, but it's nothing like a 30x dilution, which is 1 part of the original substance dissolved in 1,000,000,000,000,000,000,000,000,000,000 parts of inert substance.

Which for most of us qualifies as "really fucking dilute," but those of you who know some chemistry might recognize that this dilution far surpasses Avogadro's Limit -- because once you have done a 1-in-10 serial dilution 23 times, you have (on average) one molecule of the original substance left.  Any further dilution, and you essentially have nothing there but the inert carrier.

Not that the original substance does what the homeopaths say it does in the first place.  But considering that they claim that the more dilute a substance is, the stronger it is, I'm not sure we should be splitting scientific hairs, here.

If you paw around the Clever H site, you find the following disclaimer:
All content on this website is intended as an adjunct to, not a substitute for professional homeopathic and/or medical care. 
No publication of Clever H. or its sub-pages should be interpreted as a means of diagnosis or treatment for any disease or condition, and the articles published at Clever H. by no means claim completeness of information. 
For a medical diagnosis or treatment a licensed medical professional should be consulted. Homeopathic treatments should only be undertaken under direct guidance and care of a professionally trained Health Care Professional specialized in the services described.
Maybe it's just me, but "A noticeable difference will be seen on the skin’s appearance and even aches and pains will improve.  When the lymphatic system is functioning at its best, weight loss and cellulite will be in control and the immune system will be functioning optimally" sure sounds like a recommendation for a "treatment of [a] disease or condition."

I keep hoping that the homeopaths and other purveyors of pseudo-medical quackery will be so widely known for what they are that they'll go out of business, but (much as it pains me to admit it) homeopathic "remedies" are still on the shelves of our local pharmacy.  Including some that are 30x dilutions (or even more dilute, and therefore stronger).  This means that people are buying them, and using them in the hopes of treating conditions for which they should be seeking out legitimate medical care.  Bringing me back once again to the site What's the Harm -- wherein you will find that a lack of critical thinking skills, with regards to your own health, can be very, very dangerous.

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This week's Skeptophilia book recommendation is a classic: Richard Dawkins's The Blind Watchmaker.  This book is, in my opinion, the most lucid and readable exposition of the evolutionary model ever written, and along the way takes down the arguments for Intelligent Design a piece at a time.  I realize Dawkins is a controversial figure, given his no-quarter-given approach to religious claims, but even if you don't accept the scientific model yourself, you owe it to yourself to see what the evolutionary biologists are actually saying.

[If you purchase the book from Amazon using the image/link below, part of the proceeds goes to supporting Skeptophilia!]




Tuesday, May 8, 2018

Astrohomeopathy

Because there's no idiotic idea that can't be made even more ridiculous by blending it with another idiotic idea, today we consider "astro-homeopathy."

If you're thinking, "Wait... that can't mean what it seems to...", unfortunately, yes, it does.  There actually are people who are prescribing homeopathic "remedies" based on your astrological sign.

As we're told over at the the site Ashwini Homeopathy Holistic Healing:
Each planet and its sign have certain characteristics, which may be weak or strong, depending on their placement in the horoscope.  By matching these characteristics of the planets and their signs with the symptoms of Homoeopathic [sic] remedies, it is possible to connect them in order to select the right medicine.
It's explained even more fully over at the site Mystic Scripts:
Astro homeopathy is based on a very unique idea of relating homeopathy with astrology.  Many people follow the astrohomeopathy principles and lead a healthy life.  You can also try astro homeopathy healing methods so that you can lead a life free from health hazards and fitness problems.

Astrology and homeopathy are bridged in astro homeopathy.  An astrohomeopathy reading for you finds out your sun sign and the body parts related to your sign of the zodiac, and tells you the health problems you have the possibility to suffer from (if, of course, there is [sic] any).  In addition, you also come to know the homeopathic remedies for the health problems.
On this site there is a link where you can get your own free astrohomeopathy reading, so of course, I had to do it.  So I entered my birthdate, and this is what I got:
You are intense and ong [sic] willed people who have a very determined nature.  You are powerful and full of energy.  You may seem very calm on the surface but inside, you have a lot of latent aggression. You are very thoughtful and good company, but you are more than that meets the eye.  You seem to be detached from events but actually keep a careful track of what is happening.  You are very sensitive, which leads you to being short tempered.  You have great will power and will achieve your goals if focused.  You are highly motivated individuals who are very resourceful and passionate in your dealings.  You have ong [sic] powers of reasoning and if put to the right use, you will reach the top in no time.
Man, if being short-tempered and having latent aggression are my "positive traits," I can barely wait to see what my negative ones are.  At least I'm a very "ong" person.  That's good, right?

L'homme zodiacal from Les très riches heures du Duc de Berry (ca. 1410) [Image is in the Public Domain]

Now, for the bad news -- my "negative traits:"
Your bluntness may hurt a lot of people.  You may get too involved and probe into issues, which doesn't concern them.  You may be temperamental, making them very difficult to get along with.  You believe you can achieve a lot in life, but just talk and don't do anything as you may have become over confident.  You may be arrogant and jealous of others' achievements.  You do no [sic] trust people and are always suspicious.  Your secretive nature may create problems.  Also you may turn violent at the blink of an eye.
If wanting to flip a table when I'm reading paragraph after paragraph of horseshit constitutes being "temperamental and violent," then guilty as charged.

Then there's the homeopathy part.  Apparently, given my birth sign, what I need is a "remedy" made from plaster of Paris.  I shit you not.  And wait till you read why:
CALCAREA SULPHUREA (Sulphate of Lime, Plaster of Paris) -- Scorpio exerts influence over the sexual organs and as such the pure Scorpions are prone to suffer form infections and problems in their sex organs.  They are susceptible to skin eruptions on the genitals, cystitis and diseases of the urinary tract along with venereal infections.
I don't know about you, but that's enough to make me walk around in a protective crouch for the rest of the day.  The remedy, by the way, "has no side effects," which is a relief, although a more accurate way to put it is "has no effects whatsoever."

Oh, and my lucky numbers are 2 and 4, my lucky colors are burgundy and black, and my lucky day is Tuesday (which is today!  Yay!).

I'm also told that famous persons I'm supposedly similar to include John Keats, Julia Roberts, Bill Gates, and Pablo Picasso.  And I'm sure you can see immediately how alike those four are.

Anyhow, I'm off to take my plaster of Paris pills so my sexual organs don't erupt, and so my arrogant and overconfident nature doesn't cloud my powers of reasoning and bring to the surface my latent aggression.  I hate it when that happens.

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This week's featured book on Skeptophilia is Flim-Flam!, by the grand old man of skepticism and critical thinking, James Randi.  Randi was a stage magician before he devoted his career to unmasking charlatans, so he of all people knows how easy it is to fool the unwary.  His book is a highly entertaining exercise in learning not to believe what you see -- especially when someone is trying to sell you something.






Thursday, April 19, 2018

Diluted nonsense

Every time I think homeopathy can't get more ridiculous, I turn out to be wrong.

I thought they'd plunged to the bottom of the Crazy Barrel with their announcement of a remedy called "homeopathic water."  This is, unfortunately, exactly what it sounds like.  It's water diluted with water, then shaken up, then diluted again and again.

With water.

So I thought, "This is it.  It can't get any loonier than that."

I was very, very wrong, and found out the depth of my mistake at Frank van der Kooy's site Complementary Medicine -- Exposing Academic Charlatans, wherein we find out that watering water down with water is far from the nuttiest thing the homeopaths make "remedies" from.

Here are a few things that van der Kooy found out form the basis of a homeopathic remedy:
  1. Black holes.  Yes, I mean the astronomical object, and yes, I'm serious.  An amateur astronomer put a vial of alcohol on a telescope aimed at the location of Cygnus X-1, the first black hole to be discovered.  My guess is that said astronomer had consumed a good bit of the alcohol first, and that's how he got the idea.  But after the vial had sat there for a while, and gotten saturated with the Essence of Black Hole, it was diluted to "30C" (known to the rest of us as one part in ten to the thirtieth power).  The homeopaths say if you consume it, it causes you to have a "drawing inward" sensation (because, I'm guessing, black holes pull stuff in).  One person who tested it said it felt like her teeth were being pulled backwards into her head.  Why this is supposed to be a good thing, I have no idea.
  2. Vacuum.  I'm not talking about the machine, I'm talking about the physical phenomenon.  I don't have a clue how you would mix a vacuum in water, nor what "diluting a vacuum" even means.  The "practitioner," however, says it's really good for treating the flu.
  3. The note "F."  Why F and not C# or Ab or something, I'm not sure, but apparently this is made by playing the note F at some water, then diluting it a bunch.  After that, it's good as a "tranquilizer" and "cardiac regulator."
  4. The south pole of a magnet.  Again, I'm not sure what's special about the south pole, but if you somehow introduce south-poliness into some water, you can use it to treat frostbite, hernia, dislocations, ingrown toenails, and "levitation."  (I feel obliged at this point to state again for the record that I'm not making this up.)
  5. Dog shit.  Supposedly, consuming diluted dog shit helps you get over feelings of self-disgust, which you would definitely need if you're consuming diluted dog shit.  It also helps if you dream about dogs, or "feel like your arms and legs are getting shorter," which I didn't know was even a thing.
  6. The Berlin Wall.  A remedy made from a chunk of the Wall -- and not to beat this point to death, but the Wall piece was shaken up in water and diluted a gazillion times -- is good for treating despair.  I could use some right now, because after reading about how many people believe this kind of thing works, I'm inclined to agree with Professor Farnsworth.


Van der Kooy has other examples, and some really amusing commentary, so I urge you to check out his website, as long as you don't mind further declines in your opinion about the general intelligence of the human species.

Once again, I'm struck not by people coming up with this nonsense -- because selling nonsense to make money has been a pastime of humans for a long, long time.  What gets me is that apparently people read this stuff, and don't have the response that I did, which is to snort derisively and say, "You have got to be fucking kidding me."  Instead, they pull out their credit cards and start buying.

So here we are again, shaking our heads in utter bafflement.  At least I hope you are.  I hope you haven't read this and said, "What's he pissing and moaning for?  This all makes perfect sense."  If that was, in fact, your response, please don't tell me about it.  Now y'all will have to excuse me, because I'm going to go take my anti-despair Berlin Wall remedy, mixed well into a double scotch.  That might actually have some effect.

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This week's Featured Book on Skeptophilia:

This week I'm featuring a classic: Carl Sagan's The Demon-Haunted World: Science as a Candle in the Dark.  Sagan, famous for his work on the series Cosmos, here addresses the topics of pseudoscience, skepticism, credulity, and why it matters -- even to laypeople.  Lucid, sometimes funny, always fascinating.








Thursday, March 15, 2018

Closing the books on homeopathy

There comes a point when there is absolutely no reason to continue investigating a claim for which there is no evidence (or significant evidence against).  Pursuing it beyond that point is a waste of money, time, and effort, and can only be explained by people's desperation not to have their pet idea proven wrong.

That point has been reached by homeopathy.  It is useless, unscientific horseshit.  Case closed.

But if by some chance you still were unconvinced, consider the paper that was withdrawn last week from the journal Evidence-based Complementary and Alternative Medicine.  The title of the journal itself makes me wince a little; to paraphrase Tim Minchin, when alternative medicine has the support of evidence, it is thereafter known as "medicine."  But setting that aside for a moment, the paper in question was written by father/son team Aradeep and Ashim Chatterjee, and claimed that the homeopathic remedy "psorinum" was effective in treating cancer.

Without even knowing what "psorinum" is, any claim that a homeopathic "remedy" can cure cancer is about as close to medical fraud as you can skate without committing an actual crime.  If you don't know how "remedies" are created, the quick explanation is that you take a substance of some kind and dilute it past the point where there is any of it left, and then use the resulting water to treat whatever condition has symptoms like the ones created by ingesting the original substance.

For example: the homeopathic sleep-aid "calms forté" is made by diluting caffeine.  I shit you not.

[image courtesy of the Wikimedia Commons]

In the case of "psorinum," however, we have an additional level of "what the fuck?" to add; the "remedy" is made by diluting...

... wait for it...

... fluid from the blisters of someone who has scabies.

I feel obliged to say at this point that I am not making this up.  The site Homeopathy Plus, which is the source of the link above, says the following about "psorinum:"
Those who need Psorinum usually lack vitality and are prone to mental disturbances.  They catch infections easily, especially colds, and recover slowly.  Skin complaints are common and if unattended will be dirty and offensive but these days with frequent bathing and access to steroids, are less likely to be so.  The person is also likely to be anxious about health, work, poverty and the future which leads to depression, despair and sometimes, suicidal thoughts.
You read that right.  If you're depressed because you're poor, the treatment is to ingest serially-diluted scabies pus.

Anyhow, the Chatterjees wrote a paper suggesting that "psorinum" could treat cancer, and evidently that was too much even for Evidence-based Complementary and Alternative Medicine.  When it was found that (1) the "ethics board" that cleared the study the paper was based on was identical to the Board of Directors of a clinic the Chatterjees owned, and (2) both the father and the son were practicing medicine without a license, it was too much for the authorities, too, and the pair were arrested.

This, unfortunately, is not a unique occurrence.  Papers supporting homeopathy have, one and all, been shown to be cherry-picked, if not outright fraudulent.  100% of the controlled scientific studies of homeopathic claims have resulted in zero evidence in favor.

So enough people-hours and research grant money has been wasted on this.  Homeopathy was a ridiculous claim from the get-go, but it was only fair to test it.  The research community did so.  It failed.

Case closed.

Now, the next step is to get those useless sugar pills off the shelves at CVS and other pharmacies.  I know the principle of caveat emptor applies, and if you're choosing to waste your money on fake treatments, you deserve what you get.  But the companies that make this stuff are profiting off the general public's gullibility and ignorance, people are taking quack remedies for serious conditions instead of seeking out legitimate medical help, and the Food & Drug Administration needs to put a stop to it.

As far as the Chatterjees go -- to quote a friend of mine, "I hope they bring them some 'psorinum' sugar pills in jail to cure their 'anxiety about the future.'"  To which I can only add: "Would you like some highly-diluted skin lotion for that burn?"

Thursday, December 1, 2016

Accidentally active

In today's contribution from the Unintentional Irony Department, we have: a New Jersey pharmaceuticals company has issued a recall of some homeopathic "remedies" last week because they contain actual active ingredients.

I wish I was kidding about this. "CVS Homeopathic Infants' Teething Tablets", "Kids Relief Homeopathic Ear Relief Oral Liquid" and "CVS Homeopathic Kids' Ear Relief Liquid," all produced by Raritan Pharmaceuticals and marketed nationwide, are being recalled because they contain "varying levels of belladonna," better known as deadly nightshade.

"The recall is a precautionary action," said Sushant Pradhan, a Raritan Pharmaceuticals representative. "The products contain only about a nanogram of belladonna, which is not toxic to anybody."

But wait a minute.  I thought the whole point of homeopathy was that the less of the original ingredients were, the more potent it becomes.  In that case, shouldn't a nanogram be a fatal dose?

[image courtesy of the Wikimedia Commons]

In any case, the company wants everyone to know that there haven't been any reports of adverse effects, that the recall was purely to prevent any problems.  And the most amusing thing about all of this is that it's not the first time it's happened; two years ago, a different company had to recall some homeopathic products that were labeled "Penicillum" because they actually contained Penicillum, the mold that produces penicillin, and there was a chance a person with a penicillin allergy could have a reaction, instead of simply consuming a sugar pill, which was apparently their intent.

What pisses me off about all of this is the kid-gloves approach that CNN used in its report (linked above).  Here's an actual quote:
Pradhan acknowledged that there can be a wide range of belladonna levels across homeopathic treatments outside of the recalled products.  Belladonna is used in several alternative medicines: it can be found in homeopathic eye drops and as a cure for upset stomach, he said. 
"This is not your typical medicine," and homeopathic treatments should be used with caution, Pradhan said.  People who use homeopathic treatments may be seeking a healthier, more natural remedy than with modern medicine, he explained, but alternative cures risk being less regulated than standard medications.
No, this is "not your typical medicine" because it's not a medicine at all.  It's a completely useless hyper-diluted bottle of water or sugar pills.  So they may be "seeking a healthier, more natural remedy," but what they're getting is completely worthless except insofar as it might trigger the placebo effect.

Appalling, then, that places like CVS still stock the stuff.  Taking homeopathic "remedies" can stop people from seeking medical care when they need it, and the profit motive still keeps it on the shelves.  (And people accuse "Big Pharma" of being motivated by money.)  If you doubt that homeopathic "remedies" are a fraud and cause damage, take a look at the site What's the Harm?, that documents 437 cases (and counting) of people who have been seriously injured or killed by taking homeopathic "remedies" instead of seeking competent medical attention.

So this started out being funny, and ended up being not so funny after all.  In any case, if the CNN story doesn't put people on notice that they're been hoodwinked, hopefully What's the Harm? will.  I live in hope that the public will start making decisions based on science, facts, and rationality rather than superstitious hocus-pocus, but it's evident from this that we still have a ways to go.

Thursday, September 29, 2016

I smell a rat

I think I've made my position on GMOs plain enough, but let me just be up front about it right out of the starting gate.

There is nothing intrinsically dangerous about genetic modification.  Since each GMO involves messing with a different genetic substructure, the results will be different each time -- and therefore will require separate testing for safety.  The vast majority of GMOs have been extensively tested for deleterious human health effects, and almost all of those have proven safe (the ones that weren't never reached market).

So GMOs are, overall, as safe as any other agricultural practice -- i.e. not 100% foolproof, but with appropriate study, not something that deserves the automatic stigma the term has accrued.

There are a great many people who don't see it that way.  One of the most vocal is Gilles-Éric Séralini, who made headlines back in 2007 with a study that alleged that rats fed genetically modified corn showed blood and liver abnormalities.  When the study was published and other scientists attempted to replicate it (and failed), the results of Séralini's study were attributed to "normal biological variation (for the species in question)."

[image courtesy of the Wikimedia Commons]

Undeterred, Séralini went on in 2012 to publish a paper in Food and Chemical Toxicology about long-term toxicity of glyphosate (RoundUp) that is still the go-to research for the anti-Monsanto crowd.  He claimed that rats dosed with glyphosate developed large tumors and other abnormalities.  But that study, too, failed in attempts to replicate it, and it was withdrawn from FCT, with the editor-in-chief stating that the results were "inconclusive."

So if you smell a rat with respect to Séralini and his alleged studies, you're not alone.

But there's no damage to your reputation that can't be made worse, and Séralini took that dubious path last week -- with a "study" that claims that a homeopathic remedy can protect you from the negative effects of RoundUp.

So, to put it bluntly: a sugar pill can help you fight off the health problems caused by something that probably doesn't cause health problems, at least in the dosages that most of us would ordinarily be exposed to.

Being that such research -- if I can dignify it by that name -- would never pass peer review, Séralini went right to a pay-to-play open-source alt-med journal called BMC Complementary and Alternative Medicine.  Steven Savage, a plant pathologist, had the following to say about the study:
The dose is absurd.  They gave the animals the equivalent of what could be in the spray tank including the surfactants and the a.i. (active ingredients).  If glyphosate or its AMPA metabolite ever end up in a food it is at extremely low concentrations and never with the surfactant.  Unless you were a farmer or gardener who routinely drinks from the spray tank over eight days, this study is meaningless.
Furthermore, Andrew Porterfield, who wrote the scathing critique of Séralini I linked above, pointed out an additional problem:
Scientists have been sharply critical of the study’s methodology and conclusions... the paper has no discussion on the natural variability in locomotion or physiological parameters, making it impossible to tell if anything was truly wrong with any of the animals.
And if that weren't bad enough, Séralini proposes to counteract these most-likely-nonexistent health effects with pills that have been diluted past Avogadro's Limit -- i.e., the point where there is even a single molecule of the original substance left.  There have been dozens of controlled studies of the efficacy of homeopathy, and none of them -- not one -- have shown that it has any effect at all except as a placebo.

So we have doubtful health problems in animals that were not evaluated beforehand for health problems being treated by worthless "remedies" that have been shown to have zero effect in controlled studies.

Of course, considering how powerful confirmation bias is, I'm not expecting this to convince anyone who wasn't already convinced.  I will say, however, that we'd be in a lot better shape as a species if we relied more on reason, logic, and evidence -- and less on our preconceived notions of how we'd like the world to be.