Skeptophilia (skep-to-fil-i-a) (n.) - the love of logical thought, skepticism, and thinking critically. Being an exploration of the applications of skeptical thinking to the world at large, with periodic excursions into linguistics, music, politics, cryptozoology, and why people keep seeing the face of Jesus on grilled cheese sandwiches.
Showing posts with label hydroxychloroquine. Show all posts
Showing posts with label hydroxychloroquine. Show all posts

Wednesday, August 19, 2020

Scooting past the reviewers

If there's one piece of advice I have for anyone trying to stay informed, it is: check your sources.

Unfortunately, these days, that takes more than just a quick look, or a recommendation from someone with authority.  After all, just two days ago Donald Trump tweeted that Fox News wasn't right-wing enough for him, that all of his faithful MAGA followers should troop on over to OANN (One America News Network),  that it was the only news source that was "fair and balanced."  Of course, this was transparent enough; in Trump-speak, "fair and balanced" means "willing to kiss Trump's ass on a daily basis."  OANN is a far-right outlet allied to sites like Breitbart -- and let's face it, anything to the right of Fox News isn't even within hailing distance of unbiased.

So "sounds like a reliable source" is itself unreliable.  As an example, take the paper that appeared last week, authored by Mathieu Edouard Rebeaud (University of Lausanne), Valentin Ruggeri (University of Grenoble), Michaël Rochoy (University of Lille). and Florian Cova (University of Geneva).  I won't tell you the title, but leap right in with an excerpt:
As the number of push-scooters has been rising in France, so has the number of push-scooters accidents.  Some of these accidents have proven to be deadly and previous YouTube™ and Dropbox© studies have warned against the deadly potential of push-scooters [1].  For a comparison, only three Chinese people had died from the novel coronavirus SARS-CoV-2 at the end of 2019 [2].  It is therefore important to reflect on the use of push-scooters through an accurate and ethical cost-benefit analysis.

Use and promotion of push-scooters have been advocated on the basis that they would contribute to the reduction and slowing of global warming.  In fact, the French scientific elite has been working on the subject and has recently argued that there was no proof of global warming, as he could not see the ice cap melt on his computer [3].  So, even if global warming was real, there are serious reasons to think that France is not affected, as global warming clearly stopped at the closed border [4].  Unfortunately, the debate is being polluted by bots, trolls and so-called experts funded by Big Trottinette to spread misinformation. Indeed, an independent study (in press on the third author’s Google Drive®) found a positive correlation between experts’ positive advocacy of push-scooters and the amount of money they received from Decathlon® (r = 3.14).  The fact that push-scooters are now a ‘generic’ means of locomotion that can be produced by anyone for a cheap price might lead people to the conclusion that no private interest is involved, but we’re not fooled, we know the truth [5].  So, it is important to diminish the increasing number of push-scooter drivers who are sacrificed on a daily basis.
The authors then go on to show that the way to combat the deadly push-scooter accident surge is through doses of hydroxychloroquine, which also shows promise in dealing with the Israeli-Palestinian conflict.  (Well, most of their research supported this.  They didn't have so much luck with Study 2.  "Study 2 was excluded from analysis and from this paper," the authors write, "as it did not provide informative results (i.e. the results we wanted)."

[Image licensed under the Creative Commons Alex Genz, Female rider on Egret One eScooter, CC BY-SA 4.0]

Also notable is that besides the four actual authors, there are also additional co-authors listed as belonging to places like "The Institute of Quick and Dirty Science of Neuneuchâtel, Switzerland" and the "Institute of Chiropteran Studies of East Timor," and one is called a "General Practitioner and Independent Seeker of Science" from Ankh-Morpork, France.

You may be thinking that this must have appeared in some kind of science spoof site like the brilliant Journal of Irreproducible Results.

You may be wrong.

This paper, titled, "SARS-CoV-2 Was Unexpectedly Deadlier than Push-scooters: Could Hydroxychloroquine be the Unique Solution?", was published in the Asian Journal of Medicine and Health.

(If you want to read it -- which I highly recommend -- you should do it soon.  My guess is that it'll be taken down before long.)

Sounds like a legitimate source, doesn't it?  You might be clued in that something was wrong if you noticed that the paper was submitted on July 24, accepted on August 11, and published on August 15 -- I say that notwithstanding the obviously goofy content from the title on, because most of the papers in the AJMH aren't blatantly off.  But if you look at stuff like this -- dates that make it clear that there was zero peer review involved -- there's no doubt left that this is one of those predatory pay-to-play journals, that will publish damn near anything if you give 'em some money.

Which, of course, was the point of the Rebeaud et al. paper.  It wasn't just to give us all a good laugh -- although it did that as well -- it was to shed some light on the way that predatory journals muddy the waters for everyone.

So back to where we started: CHECK.  YOUR.  SOURCES.  Which doesn't just mean a cursory "okay, it's a 'journal of medicine and health,' it must be reliable."  Take five minutes to do a quick search to see if there are any reviews or commentary on the journal itself.  The best thing is to find good sources that you know you can always rely on -- top-flight research journals like Science, Nature, Cell, Proceedings of the National Academy of Science, and PLOS-One, to name five -- as well as research-for-the-layperson journals like Scientific American and Discover.

If you get outside of those realms, though, caveat lector.  You never know what kind of lunacy you'll find, up to and including recommendations for taking hydroxychloroquine to prevent push-scooter accidents.

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Fan of true crime stories?  This week's Skeptophilia book recommendation of the week is for you.

In The Poisoner's Handbook:Murder and the Birth of Forensic Medicine in Jazz Age New York, by Deborah Blum, you'll find out about how forensic science got off the ground -- through the efforts of two scientists, Charles Norris and Alexander Gettler, who took on the corruption-ridden law enforcement offices of Tammany Hall in order to stop people from literally getting away with murder.

In a book that reads more like a crime thriller than it does history, Blum takes us along with Norris and Gettler as they turned crime detection into a true science, resulting in hundreds of people being brought to justice for what would otherwise have been unsolved murders.  In Blum's hands, it's a fast, brilliant read -- if you're a fan of CSI, Forensics Files, and Bones, get a copy of The Poisoner's Handbook, you won't be able to put it down.

[Note: if you purchase this book using the image/link below, part of the proceeds goes to support Skeptophilia!]




Thursday, July 30, 2020

The doctor, Donald Trump, and demon sex

As I have mentioned more than once, there's pretty good evidence lately that the aliens who are in charge of the computer simulation we're all trapped in have gotten bored and/or stoned, and now they're just fucking with us.

For example, consider Dr. Stella Immanuel.  Dr. Immanuel has recently become a darling of the pro-Trump faction for her claims that she's cured people with active COVID-19 infections through a combination of hydroxychloroquine, Zithromax (the antibiotic in the "Z-Pak"), and zinc.  She was one of the leading voices at a "summit" hosted by a group calling itself "America's Frontline Doctors," which I have to admit has more gravitas than the more accurate "America's Batshit Conspiracy Theorists."  The misinformation flew at the "summit," including not only that COVID-19 was curable using hydroxychloroquine (multiple studies have found it to have no positive effects on the course of the illness, and a plethora of nasty side effects, some of which can be fatal), but that the pandemic itself was overblown and that masks aren't necessary to prevent its spread.

Trump, of course, loves Dr. Immanuel, because her message is identical to the one he's been pushing for months.  He tweeted a link to a video of Dr. Immanuel defending her coronavirus misinformation, and Donald Jr. retweeted it, calling it a "Must watch!!!"  Then the powers-that-be at both Twitter and Facebook, showing a rare burst of ethical behavior, deleted her video, tagged tweets promoting it as "containing misinformation," and most surprising of all, locked Donald Jr.'s Twitter account for twelve hours.


Dr. Immanuel, though, follows Trump's model in more than just espousing ridiculous pseudoscience; her personal motto is apparently "Death before admitting error."  After her video was taken down, she and Trump both doubled down on her position.  Dr. Immanuel threatened divine intervention, saying that Jesus Christ would destroy Facebook's servers if the video wasn't restored.  (They didn't, and he didn't.)  Trump, on the other hand, took a more mundane approach, if not substantially more sane.  "I can tell you this, she was on air along with many other doctors," he said.  "They were big fans of hydroxychloroquine and I thought she was very impressive in the sense that from where she came, I don't know which country she comes from, but she said that she's had tremendous success with hundreds of different patients, and I thought her voice was an important voice, but I know nothing about her."

The bizarre ideas of this "important voice" go far beyond misinformation about COVID-19, however.  Dr. Immanuel is a veritable fountain of loony beliefs, which include the following:
  • The medical establishment is working on medicines that are created from extraterrestrial DNA.
  • Gynecological disorders occur when women have dreams about having sex with demons.  It's the "demon sperm" that causes the problem.
  • Wet dreams cause erectile dysfunction, once again because they're accompanied by images of having sex.  With demon women, of course.
  • The demons themselves, though, aren't just in it for the kicks, but because that's how they reproduce.  "They turn into a woman and then they sleep with the man and collect his sperm," Immanuel said in a sermon at the church she runs in Houston, Texas, called "Firepower Ministries."  "Then they turn into the man and they sleep with a woman and deposit the sperm and reproduce more of themselves."
  • She calls herself a "wealth transfer coach."  Presumably that means transferring wealth from your bank account to hers.
  • The Illuminati (of course the Illuminati are involved) are trying to destroy the world, and the main way they're doing this has to do with gay marriage.  Don't ask me how that works.
  • Part of the government is being run by aliens who are reptilian in appearance, and oddly enough, I don't think she meant Mitch McConnell.
  • Scientists are currently working on a vaccine to prevent people from being religious.
  • Even children's toys are suspect.  She calls Pokémon "eastern demons," and has a special hatred for the Magic 8-Ball, which is a "psychic object used to start children in witchcraft."  (Sorry, Dr. Immanuel, "My sources say no.")
So this is the person that Donald Trump called "spectacular" and "very respected."

Then others took up the outcry.  Jenny Beth Martin, co-founder of the Tea Party Patriots, said that because Dr. Immanuel and Donald Trump were saying the same thing, she was being "attacked, ridiculed, and discredited" in a deliberate effort to damage Trump's reputation.  (Not, apparently, because what she was saying was certifiable horseshit.)  Simone Gold, one of the leaders of America's Frontline Doctors, said that social media was committing a crime by "censoring Physicians from speaking about COVID-19 and Hydroxychloroquine."  Radio host Mark Levin criticized several media outlets, such as The Daily Beast, for being part of a "vicious smear machine" -- because they'd quoted Dr. Immanuel verbatim.

As for the doctors who refuse to prescribe hydroxychloroquine for coronavirus infections, Dr. Immanuel said, "You’re no different than a murderer.  You’re no different than Hitler."

Here we have a person who in a sane world would be looked at as a wacko, more to be pitied than censured, but because Donald Trump says he likes her, Trump-supporters nationwide suddenly act as if she's the next Jonas Salk.  (Oh, and simultaneously, they cast Dr. Anthony Fauci -- one of the world's experts in communicable disease research -- as a fool at best and an evil mastermind at worst, for saying such things as "wear a mask in public" and "don't take medications that don't work and can also kill you.")

So that's the upside-down world we currently live in.  I'd like to tell you that things will sort themselves out and that wiser and saner heads will ultimately prevail, but if there's one thing I've learned in the past four years, it's that predicting what will happen next is a loser's game.  I even tried asking the best source I have, hoping to get some clarity, desperately seeking a reason to believe that things will improve soon.

But all it would say is "Reply hazy, try again."

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Being in the middle of a pandemic, we're constantly being urged to wash our hands and/or use hand sanitizer.  It's not a bad idea, of course; multiple studies have shown that communicable diseases spread far less readily if people take the simple precaution of a thirty-second hand-washing with soap.

But as a culture, we're pretty obsessed with cleanliness.  Consider how many commercial products -- soaps, shampoos, body washes, and so on -- are dedicated solely to cleaning our skin.  Then there are all the products intended to return back to our skin and hair what the first set of products removed; the whole range of conditioners, softeners, lotions, and oils.

How much of this is necessary, or even beneficial?  That's the topic of the new book Clean: The New Science of Skin by doctor and journalist James Hamblin, who considers all of this and more -- the role of hyper-cleanliness in allergies, asthma, and eczema, and fascinating and recently-discovered information about our skin microbiome, the bacteria that colonize our skin and which are actually beneficial to our overall health.  Along the way, he questions things a lot of us take for granted... such as whether we should be showering daily.

It's a fascinating read, and looks at the question from a data-based, scientific standpoint.  Hamblin has put together the most recent evidence on how we should treat the surfaces of our own bodies -- and asks questions that are sure to generate a wealth of discussion.

[Note: if you purchase this book using the image/link below, part of the proceeds goes to support Skeptophilia!]