One of the most striking pieces from neuroscientist David Eagleman's brilliant TED Talk "Can We Create New Senses for Humans?" centers around what is really happening when we experience something.
Regardless what it feels like, all that's going on -- the internal reality, as it were -- are some fairly weak voltage changes bouncing around in the brain. The brain is locked inside the skull, and on its own is blind and deaf. It needs the sense organs (Eagleman calls them our "peripherals") to send electrical signals in via input nerves to the right places in the brain, and that stimulates changes in the voltage in those areas.
That's it. Everything you've ever experienced -- good and bad, pleasant and unpleasant -- boils down to that. And if something messes around with any step in that process, that altered electrical state in the brain becomes the basis of what you see, hear, feel, and think. If the wiring is faulty (thought by some researchers to be the cause of the peculiar disorder synesthesia), if there's a problem with the levels of neurotransmitters, the chemicals that either pass signals along or else block them (probably involved in schizophrenia, depression, and anxiety, among others), or if you've taken drugs that change the electrical activity of the brain -- that becomes your reality.
I was reminded of this sobering observation when I read an article sent to me my a friend and loyal reader of Skeptophilia. Entitled, "Have Scientists Found the Source of Out-of-Body Experiences?", it describes research into a part of the cerebrum called the anterior precuneus, which appears to be involved in our sensations of conscious awareness. Neuroscientist Josef Parvizi of Stanford University was working with epilepsy patients who were experiencing drug-resistant seizures, and found that when the anterior precuneus was electrically stimulated (the patients already had electrodes implanted in their brains to try to reduce the frequency and severity of their seizures), they had sensations of floating, and of dissociation and disorientation.
"All of them reported something weird happening to their sense of physical self," Parvizi said in an interview in Scope, Stanford Medicine’s blog. "In fact, three of them reported a clear sense of depersonalization, similar to taking psychedelics."****************************************




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