Skeptophilia (skep-to-fil-i-a) (n.) - the love of logical thought, skepticism, and thinking critically. Being an exploration of the applications of skeptical thinking to the world at large, with periodic excursions into linguistics, music, politics, cryptozoology, and why people keep seeing the face of Jesus on grilled cheese sandwiches.
Showing posts with label epidemiology. Show all posts
Showing posts with label epidemiology. Show all posts

Saturday, October 4, 2014

Worldviews, conspiracies, and Ebola

Sometimes I don't think that skeptics and conspiracy theorists speak the same language.

Oh, we're both saying words that the other understands; but there's a fundamental disconnect.  The worldviews are so incompatible that what one says makes no sense whatsoever to the other.

Take, for example, the change in the language in a statement on Ebola from the Public Health Agency of Canada.  Here's the original statement, with the relevant passage highlighted:
MODE OF TRANSMISSION: In an outbreak, it is hypothesized that the first patient becomes infected as a result of contact with an infected animal. Person-to-person transmission occurs via close personal contact with an infected individual or their body fluids during the late stages of infection or after death. Nosocomial infections can occur through contact with infected body fluids due to the reuse of unsterilized syringes, needles, or other medical equipment contaminated with these fluids. Humans may be infected by handling sick or dead non-human primates and are also at risk when handling the bodies of deceased humans in preparation for funerals, suggesting possible transmission through aerosol droplets. In the laboratory, infection through small-particle aerosols has been demonstrated in primates, and airborne spread among humans is strongly suspected, although it has not yet been conclusively demonstrated. The importance of this route of transmission is not clear. Poor hygienic conditions can aid the spread of the virus.
And the new statement, as of August 2014:
MODE OF TRANSMISSION: In an outbreak, it is hypothesized that the first patient becomes infected as a result of contact with an infected animal. Person-to-person transmission occurs via close personal contact with an infected individual or their body fluids during the late stages of infection or after death. Nosocomial infections can occur through contact with infected body fluids for example due to the reuse of unsterilized syringes, needles, or other medical equipment contaminated with these fluids. Humans may be infected by handling sick or dead non-human primates and are also at risk when handling the bodies of deceased humans in preparation for funerals.

In laboratory settings, non-human primates exposed to aerosolized ebolavirus from pigs have become infected, however, airborne transmission has not been demonstrated between non-human primates. Viral shedding has been observed in nasopharyngeal secretions and rectal swabs of pigs following experimental inoculation.
So what did I immediately think, upon finding out about this?  That the agency realized the information in the original statement was erroneous, and updated it to reflect the most recent research.

[image courtesy of the Wikimedia Commons]

What did the conspiracy theorists think?  Do I even need to tell you?  Here's a variety of responses, collected from a variety of conspiracy sites, commenting on the change:
They're pulling the wool over our eyes.  They've known that ebola can be transmitted airborne for years, but they don't want the public to know, because the panic will bring down government.  I'm surprised they let it slip that long. 
Any time there's a change in official government policy, be suspicious. 
If you people don't wake up to what the government is doing, it will be too late to stop a pandemic. 
They never want you to have any real information, so they keep shifting their ground.  It's a classic bait-and-switch, so you never see the catastrophe coming.
And my favorite one:
If you let yourself get this government death plague, you have only yourself to blame.
I must say, if I ever start a punk band, I'm going to call it "Government Death Plague."

Not that that's likely.  But still.

So anyway.  Two things about this strike me: (1) that presented with exactly the same facts, I came up with an entirely different conclusion than the conspiracy theorists did; and (2) that there is very likely no argument on either side that would convince the other that they were wrong.

That's what I mean about speaking different languages.  And I wonder where these radically different perspectives come from?  Is it as simple as optimism versus pessimism?  Or is it something more complicated than that?  It'd be interesting to do a comparative personality study on skeptics and conspiracy theorists.

But the conspiracy theorists would never go for that, of course.  They'd think the Illuminati were collecting background information on them so as to make it easier to round them up into FEMA camps.

You can't win.

Monday, August 4, 2014

Ebola, epidemics, and the danger of making decisions out of fear

The news has been filled in the last couple of weeks with stories about the ongoing epidemic of Ebola fever in west Africa.  And certainly, there's a lot here that's newsworthy.  An emerging virus, long known for lightning-fast outbreaks that killed whole villages deep in the jungle and then disappeared as fast as it came, has finally appeared in two large cities, Conakry, Guinea and Monrovia, Liberia.  The disease itself is terrifying; it has a mortality rate of between 60% and 90%, depending on the strain, and kills victims when their blood stops clotting, causing them to "bleed out."

Which, unfortunately, is exactly what it sounds like, and about which I won't say anything further out of respect for my more sensitive readers.

The Ebola virus [image courtesy of the Wikimedia Commons]

This epidemic has two of the features that tend to make people overestimate risk: (1) it's gruesome; and (2) it's novel.  We react most strongly to things that are new, unfamiliar, and scary, and Ebola certainly qualifies.  And it is a regrettable feature of human nature that when our fear centers are engaged, we make dumb decisions.

Let's start with the desperate desire on the part of people who are scared by the virus to protect themselves against it, although the current state of affairs is that there is no vaccine, and no way to prevent catching it except by avoiding close contact with ill individuals.  This hasn't stopped the hucksters from seeing this as an opportunity to extract money from the gullible.  Starting with the site Essential Oils For the Win!, which makes the bizarre claim that we "shouldn't be scared of Ebola" because "it can be treated with the proper essential oil."

Well, it's true that there's probably no real reason to be scared of Ebola unless you're planning on a visit to west Africa, but I would invite the owner of this website to go there himself armed only with a vial of lavender oil, and see how confident he feels then.  That the author of the website has a slim grasp of science, and probably reality as well, is reinforced by the diagram wherein we're shown that essential oils work because unlike conventional medicines, they are good at "penetrating cell walls."

So it's reassuring to know that your tomato plants and petunias won't get Ebola.  As for us, being animals, our cells don't even have cell walls, so I'm thinking that I'd rather see what the actual scientists come up with.

Which definitely does not include the homeopaths, who are also weighing in.  No worries, they say... according to an article at The Daily Kos, they already have their "remedies" at the ready!
Dr. Gail Derin studied the symptoms of Ebola Zaire, the most deadly of the three that can infect human beings. Dr. Vickie Menear, M.D. and homeopath, found that the remedy that most closely fit the symptoms of the 1914 "flu" virus, Crolatus horridus, also fits the Ebola virus nearly 95% symptom-wise! Thanks go to these doctors for coming up with the following remedies:
1. Crolatus horridus (rattlesnake venom) 2. Bothrops (yellow viper) 3. Lachesis (bushmaster snake) 4. Phosphorus 5. Mercurius Corrosivus
Yup.  Here's their logic: because the venom of "Crolatus horridus" is 95% fatal, and so was the Spanish flu, and so is Ebola Zaire, the venom must be useful for treating Ebola.  Only, of course, if you dilute it until all the venom is gone.

I only have three objections to this:
  1. I'm assuming you're talking about the timber rattlesnake, which is in the genus "Crotalus," not "Crolatus."  And the Spanish flu occurred in 1918, not 1914.  But those may be minor points.
  2. Many other things have a very high fatality rate, including gunshots to the head.  Does this mean you could also add a sixth "remedy" for Ebola, Essentius Leadus Bulletus, made by shaking up bullets in water and diluting it a gazillion times?
  3. Are you people insane?
 The fear tactics didn't stop with loony cures, though; the politicians began to weigh in, and (of course) attempt use the whole thing to score political capital.  And once again, they are targeting people who are thinking with their adrenal glands rather than their brains.  No one is as good at that as the inimitable Michele Bachmann, who instead of fading into richly-deserved obscurity, has kept herself center stage with commentary like this:
People from Yemen, Iran, Iraq and other terrorist nations are making their way up through America’s southern border because they see that it’s a green light, they can easily get in.  Not only people with potentially terrorist activities, but also very dangerous weapons are going to cross our border in addition to very dangerous drugs, and also life-threatening diseases, potentially including Ebola and other diseases like that... 
Now President Obama is trying to bring all of those foreign nationals, those illegal aliens to the country and he has said that he will put them in the foster care system.  That's more kids that you can see how - we can't imagine doing this, but if you have a hospital and they are going to get millions of dollars in government grants if they can conduct medical research on somebody, and a Ward of the state can't say 'no,' a little kid can't say 'no' if they're a Ward of the state; so here you could have this institution getting millions of dollars from our government to do medical experimentation and a kid can't even say 'no.'  It's sick.
So, let's see if we can parse this.  People from the Middle East are coming in across the border between the United States in Mexico, and they did so by coming via Liberia, where they picked up Ebola, and they're going to pass that disease along to innocent Americans, but some of the kids got infected along the way, and now President Obama is going to place them in medical facilities where they will be experimented upon in unimaginably cruel ways.

Is it just me, or does Michele Bachmann seem to have a quarter-cup of PopRocks where the rest of us have a brain?

 What I find ironic, here, is that people are flying into a panic over a disease that (1) is rather hard to catch, and (2) has caused only 500 deaths thus far.  I say "only" to highlight the contrast with another disease, measles -- which according to the World Health Organization, killed 122,000 people in 2012 and is set to break that record this year, despite the fact that it is completely preventable by a safe and effective vaccine.

Oh, but we've all heard of measles.  So it can't be that bad, right?

And if you are still unconvinced that vaccination is the best way to go -- swayed, perhaps, by claims that the most recent measles outbreaks in the United States were among the vaccinated -- take a look at this brilliant explanation over at The LymphoSite, which explains why even if vaccines have some side effects and sometimes do not work, we still should all be vaccinated.

All of which re-emphasizes that we're better off considering actual facts, and listening to actual scientists, rather than falling prey to hucksters or listening to loons like Michele Bachmann.  Which means engaging our brains, and trying to think past our fears.

Thursday, May 16, 2013

The Welsh measles conspiracy

If, as I do, you have strong feelings about the irresponsibility of the anti-vaxxer movement, and the mountain of science that they ignore in order to bolster their beliefs that vaccination is dangerous, I recommend not reading this post.  Just reading the background material for it means that I'm probably going to have to double up on my high blood pressure medication today.

Because now the anti-vaxxers are claiming that the measles epidemic in Wales this year, in which 700 people were sickened and one killed by a disease that is 100% preventable, was faked.

Yes, you read that right.  Heidi Stevenson, writing for Gaia Health, has a stomach-turning "exposé" that begins as follows:

The Great Measles Epidemic of Wales—the one that’s being used to stampede sheeple into vaccine clinics for the MMR jab—never happened. Seriously! It was faked. The actual data from the Welsh government on cases of measles proves it.
Here's her "proof:"
The fact is that, though 446 measles notifications were made between 1 January and 31 March of this year, those were merely reports. The reality is that only 26 cases were actually confirmed!
You may have noted that this faux measles epidemic started in November, and the figures for last year weren’t included. However, that doesn’t help make the case for an epidemic, or even come close to the claim that 83 people had to be hospitalized for measles. You see, the total number of confirmed measles cases in Wales for all of 2012 was 14. So, adding 14 for all of 2012 to 26 for the first three months of this year, we get a total of 40 confirmed cases of measles—less than half the falsely reported 83 hospitalizations!
 The actual reason for the discrepancy was picked up on almost immediately, with one of the first comments on the story reading as follows:
Note that only the minority of measles test samples are sent to Welsh labs.

So in conclusion it shouldn't be surprising if the lab confirmed figures are low at present because the majority of samples are sent to English labs for confirmation and are not included in the All Wales reports.

You're drawing conclusions based on at best incomplete data.
Stevenson went on the attack in the comments section, responding to the above commenter with, "But the reality is that this is not an epidemic and even if every reported case had proven to be genuine measles, it would not amount to an epidemic - nor has it amounted to anything that anyone needs to fear."  She responded to another person who objected to her stance with, "You're a shill.  Goodbye."  To another, who had mentioned herd immunity and that it was "thought that a 95% vaccination rate was enough to protect the population from epidemics in most cases," Stevenson snarled back:
What garbage! It's isn't known, it's merely "thought that". The belief in how high the rate of vaccination must be to stop a disease keeps changing - it keeps going up. The fact is that no one knows if there is even such a thing as herd immunity. It's an idea, not a fact. And that 95% figure is something that was pulled out of the air. It's meaningless - nothing but a coverup for the fact that the vaccines are nowhere near as effective as they'd have you believe.

Regarding learning math: The fact is that you've just spewed out figures that prove nothing in relation to this particular issue, and most assuredly do not demonstrate that you have any knowledge of the topic - just that you are able to spew out published figures.

You aren't actually providing any information that elucidates the topic at hand - the fact that the actual number of cases of measles is a small fraction of the reported number, though the reported number has been used to declare an epidemic and push for vaccination.
 Oh, yeah, and to further trivialize the Welsh epidemic, she threw in the following "photograph:"


Hmm, herd immunity is "meaningless?"  That would certainly come as a surprise to Dr. Paul E. M. Fine, whose 1993 paper on epidemiological modeling (available here) is considered the go-to source on how a sufficient pool of immunes in a population can prevent epidemics from taking hold.  Research by Thomas L. Schlenker et al. (available here) on measles in particular concluded that "Modest improvements in low levels of immunization coverage among 2-year-olds confer substantial protection against measles outbreaks. Coverage of 80% or less may be sufficient to prevent sustained measles outbreaks in an urban community."

And on a more emotional level, perhaps Ms. Stevenson would like to discuss the matter with Cecily Johnson, an Australian woman whose unvaccinated daughter Laine Bradley contracted subacute sclerosing panencephalitis as a complication of a measles infection, and lingered for five years, unable to speak, unable to feed, clothe, or wash herself, before dying at age twelve.

The long and short of it is that the actual research shows what we've known for years.  Vaccination has an extremely low rate of complications, while the complications from what are now entirely preventable diseases -- measles, polio, diphtheria, typhoid -- are often debilitating and sometimes fatal.  No medical intervention is 100% safe, and if you scour the records you can find cases of bad side effects (mostly allergic reactions).  But if you weigh those against the millions of people who are now alive because of vaccines, the choice is obvious.

At least, it is to me.  It apparently isn't to Stevenson and others in the anti-vaxxer movement.  Maybe it's because any quantification of the lives saved by vaccines is always going to be a guess -- it's not like you can look at someone and say, "If you hadn't been vaccinated, you'd have died at age six of diphtheria."

But all you have to do is to look into historical records to gain that perspective.  One of my hobbies is genealogy, and being that my family is from the French part of southern Louisiana, I own several books of church and courthouse record abstracts from that region that I have used in researching my family history.  That was how I found out about the 1853 yellow fever epidemic that struck southeastern Louisiana, costing thousands of lives -- the records are there, the chronicles of individuals who were killed by that gruesome disease:
Boutary, Adela Marie, wife of Théophile Daunes, d. 10 Sept. 1853 at age 20 years during yellow fever epidemic (Thibodaux Church: vol. 1, death record #55)
Himel, Mélasie d. 17 Sept. 1853 at age 16 years during yellow fever epidemic (Thibodaux Church: vol. 1, death record #92)
Poché, Joseph d. 3 Oct. 1853 at age 19 years during yellow fever epidemic (Thibodaux Church: vol. 1, death record #151)
Any guesses as to why we don't even have yellow fever in the United States any more?  I'll leave you to figure that one out.